Scleroderma (Acrosclerosis)

Clinical Data of Eight Patients with Acrosclerosis or Progressive Diffuse Sclerosis ( Scleroderma ) and Abnormal Electrocardiograms

LTHOUGH Heinel described the first case , of sclerodermatous heart disease in 1926, this entity did not seem to be well established until 1943, when Weiss and associates2 described and discussed the problem. Since then many articles have appeared in the literature pertaining to the clinical and pathologic aspects of the disease process known as "scleroderma." In addition, the electrocardiograph...

Electrocardiograms of ninety patients with acrosclerosis and progressive diffuse sclerosis (scleroderma).

LTHOUGH Heinel described the first case , of sclerodermatous heart disease in 1926, this entity did not seem to be well established until 1943, when Weiss and associates2 described and discussed the problem. Since then many articles have appeared in the literature pertaining to the clinical and pathologic aspects of the disease process known as "scleroderma." In addition, the electrocardiograph...

Scleroderma with Nodular Scleroderma

BACKGROUND Nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea. A biopsy from the lesion can demonstrate the scleroderma pattern, i.e., keloid pattern or mixed type. Treatment is challenging, and several treatments modalities have been reported with unsatisfactory results. MAIN OBSERVATIONS We present a case of systemic scleros...

When is scleroderma really scleroderma?

Scleroderma.

The prototypic autoimmune diseases involving skin (lupus, dermatomyositis) typically result in epithelial injury and autoantibodies to characteristic cellular antigens. Disease-specific autoantibodies are also found in scleroderma, but scleroderma is different from other cutaneous autoimmune diseases because epithelial injury does not occur. Multiple factors and combinations of factors (immune ...